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Mahesh

11/04/23 13:30 PM IST

10,000 Indian genomes to be sequenced by year-end

In News
  • The Genome India Project, a Centre-backed initiative to sequence 10,000 Indian human genomes and create a database, is about two-thirds.
Genome- India Project
  • The Genome India Project, which includes both Indian Institute of Science and various IITs, will encourage new efficiency in health, agribusiness, and biotech-related fields.
  • Its main goal is to create a pattern of Indian “genome sequence” reference, to properly comprehend the types and origins of illnesses that affect India’s diverse population.
  • The project seeks to create a database to gather a representative Indian genome.
  • The Human Genome Project (HGP) was an international programme which ran between 1990 to 2003 to identify and comprehend all genetic mutations. It has resulted in cutting-edge development in health and pharmaceuticals, but over 95% of the DNA specimens were of Caucasians. So it should not be considered a representative human genome.
Concerns about Genome project
  • Genetic bias in medical insurance, jobs, and other areas is probable. It might give a biological perspective on hot topics like indigenous culture, religion or ethnicity issues, and ancestry identification.
  • Although genetic engineering can heal various ailments, moral issues exist about the degree to which it may be used. There is a danger of premature genetic augmentation.
  • Permission from study participants, use of results, and related dangers all pose confidentiality concerns. There are technical and scientific hurdles to properly comprehending the possible advantages and hazards of gene sequencing. The issue of data handling and storage must be considered in light of the danger of data misuse.
  • Restricted availability to genetic analysis and preventative treatment may exacerbate existing inequalities and cause social conflicts.
Source- The Hindu

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