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Mahesh

26/04/23 06:13 AM IST

Bio-electronic uric acid detecting device

In News
  • A new flexible bio-electronic uric acid detecting device has been fabricated that can be used for various applications such as wearable sensors and point-of-care diagnostics.
About the device
  • Researchers from the Institute of Advanced Study in Science and Technology (IASST), an autonomous institute of the Department of Science and Technology (DST), fabricated this device made up of reduced phosphorene quantum dots.
  •  A new class of zero-dimensional functional nanostructures with unique physicochemical and surface properties.
  • The quantum dots show distinctive electrical performance in biomedical applications and so can be used in fabricating high-performance electrical biosensors.
  • With the increase in uric acid concentration, the current density increases and shows a maximum current of about 1.35 ×10-6 A.
  • The device so developed is simple, portable, cost-effective, and easy to fabricate for detecting uric acid with a limit of about 0.809 µM.
Uric Acid
  • Uric acid is one of the most important antioxidants that maintain blood pressure stability and reduce oxidative stress in living beings.
  • The usual range of uric acid in blood ranges from 0.14 to 0.4 mmol dm-3, and for urine, 1.5 to 4.5 mmol dm-3.
  • The fluctuation of uric acid levels due to the lack of balancing between the production and excretion causes several diseases like hyperuricemia, which in turn may lead to gout disease, type 2 diabetes, increase risk of cardiovascular diseases, Lesch–Nyhan syndrome, hypertension, and renal disorders.
Source- PIB

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