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Science & Tech.
Pradeep Kumar

07/03/21 12:03 PM IST

Detecting the effect of prolonged alcohol exposure on RBC

In news

Scientists have custom-made a platform to detect the effect of prolonged alcohol exposure on Red Blood Cells (RBC) through high-resolution measurements of their size

Details
  • The high-resolution platform that shows the reduction in size of RBCs on alcohol exposure can be tuned for a point-of-care screening of multiple conditions that alter the size and count of RBCs in blood.
  • It is known that alcohol affects RBCs, the exact physiological changes are very subtle and difficult to measure. 
  • The device made in RRI relies on the resistive pulse sensing principle.
  • The team first developed techniques for making tiny micron (1/1000th of a millimetre) sized holes or micro-pores at the tip of a glass capillary with careful fabrication, flame polishing, and image verification
Functioning
  • Cells passing through the pore created very tiny electrical pulses, which give direct and most sensitive information of cell count and volume.
  • These results may also be used to explain the lack of oxygen-carrying capability of RBC under alcohol exposure leading to blurred vision, muscular in coordination, and altered mental states from alcohol abuse.
Source: PIB

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