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Science & Tech.
Mahesh

26/08/22 11:35 AM IST

Newly identified gene could be clue to treatment of fungal infection in immuno-compromised patients

In News 
  • The gene called CSA6 has been identified in Candida albicans a fungal species infamous for causing high rates of morbidity and mortality under certain immuno-compromised conditions such as AIDS or during cancer treatment. 
Major Findings 
  • The fungal species residing in mucosal linings of the gastrointestinal and urogenital tract of healthy individuals turns into a pathogen under immuno-compromised conditions breaching the host defense causing superficial as well as life-threatening systemic infection.
  •  It identifies and elucidates the functions of a novel regulator of chromosome stability that is exclusively present in a group of medically relevant human fungal pathogens.
  • Besides, it also provides a systematic scheme for identifying genes whose products may serve as potential therapeutic interventions for fungal infections by posing lesser adverse effects on humans.
  • Hence, small molecule modulators that alter expression levels of the gene called Csa6 offer potential avenues for treatment with no side effects in humans.
Source- PIB 

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