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Mahesh

15/07/22 14:02 PM IST

WHO’s first global report on antibiotic resistance

In News 
  • WHO has released its 1st report on vaccines being developed to prevent infections caused by AMR bacteria.
  • The report aims to guide investments and research into feasible vaccines to mitigate AMR.
Major Findings 
  • The silent pandemic of antimicrobial resistance is of major growing public health concern (resulting in the death of nearly 5mn people yearly)
  • Vaccines are still effective against Pneumococcal disease (Streptococcus pneumonia), Hib (Haemophilus influenzae type b) Tuberculosis (Mycobacterium tuberculosis) and Typhoid fever (Salmonella Typhi).
  • Current Bacillus Calmette-Guérin (BCG) vaccines against tuberculosis (TB) do not adequately protect against TB, therefore the development of more effective vaccines against TB should be accelerated.
Recommendations 
  • Equitable and global access to the vaccines that already exist
  • The lessons from Covid 19 vaccine development and mRNA vaccines offer unique opportunities to explore for development of vaccines against bacteria
  • Such as pathogens associated with hospital-acquired infections (HAI), difficulty in defining target population(s) among all admitted hospital patients; the cost and complexity of vaccine efficacy trials; and the lack of regulatory and/or policy precedent for vaccines against HAIs.
  • Vaccine development is expensive, and scientifically challenging, and is associated with high failure rates, and therefore, the need for support from the government and private sector.
Source- The Hindu 

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